Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep220 | Bone & Osteoporosis | ECE2017

Effects of acromegaly on bone tissue mRNA levels relevant to bone metabolism

Grebennikova Tatiana , Belaya Zhanna , Melnichenko Galina , Brovkina Olga , Nikitin Alexey , Astaf'eva Ludmila , Grigoriev Andrej , Dedov Ivan

Molecular basis of the bone disorders in patients with acromegaly are largely unknown.Objective: To investigate gene expression profiles that regulate bone metabolism in bone tissue samples from patients with acromegaly.Materials and Methods: Patients with clinically evident and biochemically proven active acromegaly and patients with hormonally inactive pituitary adenoma matched by age, sex and BMI were invited to participate. Bon...